LINZESS may relieve your IBS‑C or CIC symptoms by helping you feel less belly pain and have more frequent and complete bowel movements that are easier to pass.

Tips for success.

Now that you have your prescription for LINZESS, you may have a few questions about what to expect during treatment. Here is some helpful information about LINZESS. Use it to get off to a good start, and to have continued success on treatment.

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Filling your prescription

  • Once you get your prescription for LINZESS, your next step is to get it filled at your pharmacy. Make sure you have all your insurance cards with you. You will also need to activate your LINZESS Savings Card to take advantage of savings on your prescription. If you don't have one, get one here.
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Be proactive once a day, every day

  • Taken once daily, LINZESS can help you experience symptom improvement in as little as one week. To help you stay on track, set a daily alarm on your phone to remind you when to take your pill.
  • Take one capsule of LINZESS at the same time every day as directed by your doctor. Take LINZESS on an empty stomach, at least 30 minutes before your first meal of the day. If you miss a dose, skip the missed dose. Just take the next dose at your regular time. Do not take 2 doses at the same time.
    If you have trouble swallowing capsules, there's more than one way to take LINZESS. The capsule can be opened up and:
    - Sprinkled onto applesauce
    - Added to 30 mL of water
    Please see Medication Guide for full instructions.
  • Store LINZESS at room temperature (68°F to 77°F). It's important to keep LINZESS in the bottle it comes in. Keep the LINZESS bottle tightly closed, in a dry place, and keep the desiccant (the drying agent that looks like a small cloth packet) in the bottle. Keep LINZESS out of the reach of children.
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What to expect from treatment

  • LINZESS can relieve your symptoms over time. If you take LINZESS as directed, you may find symptom relief in about one week. This relief should continue while taking LINZESS daily. Once you stop taking LINZESS, your symptoms may return in about a week.
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Keep your doctor informed

  • Talk about how LINZESS is working for you. Share any side effects you might be experiencing. It's important for your doctor to understand how LINZESS may help you manage your IBS‑C or CIC symptoms.
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Refill on time

  • Your local pharmacy may offer refill reminders. Ask your pharmacist to sign you up.
  • Got vacation plans? Going on a business trip? Make sure you have enough medicine with you. Let your doctor or pharmacist know, so you can make sure you have what you need.

Patient stories

LINZESS may provide the relief you need

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Learn more

What is LINZESS?

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). "Idiopathic" means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

Important Risk Information
  • Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • You should not give LINZESS to children 6 years to less than 18 years of age. It may harm them.
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Before you take LINZESS, tell your doctor about your medical conditions, including if you are:
  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if LINZESS passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects

LINZESS can cause serious side effects, including diarrhea, the most common side effect, which can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

Please also see Medication Guide within full Prescribing Information.

*This offer is valid only for patients with LINZESS prescriptions. Depending on insurance coverage, most eligible patients may pay as little as $30 per prescription fill for each of up to 12 prescription fills. Check with your pharmacist for your copay discount. Maximum savings limit applies; patient out-of-pocket expense may vary. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. This offer is not valid for cash‑paying patients. Please see full Program Terms, Conditions, and Eligibility Criteria on our Saving on LINZESS page.

Show
What is LINZESS?

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). "Idiopathic" means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

Important Risk Information
  • Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • You should not give LINZESS to children 6 years to less than 18 years of age. It may harm them.
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Before you take LINZESS, tell your doctor about your medical conditions, including if you are:
  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if LINZESS passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects

LINZESS can cause serious side effects, including diarrhea, the most common side effect, which can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

Please also see Medication Guide within full Prescribing Information.

*This offer is valid only for patients with LINZESS prescriptions. Depending on insurance coverage, most eligible patients may pay as little as $30 per prescription fill for each of up to 12 prescription fills. Check with your pharmacist for your copay discount. Maximum savings limit applies; patient out-of-pocket expense may vary. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. This offer is not valid for cash‑paying patients. Please see full Program Terms, Conditions, and Eligibility Criteria on our Saving on LINZESS page.