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Young woman and man explore a palm tree–lined city street.

HOW LINZESS CAN HELP

LINZESS CAN HELP RELIEVE SYMPTOMS OF IBS-C & CIC

For adults with Irritable Bowel Syndrome with Constipation (IBS-C) or Chronic Idiopathic Constipation (CIC)

You may have tried to relieve chronic constipation through over-the-counter treatments, dietary changes, or exercise. But if your symptoms keep coming back, it may be time to consider LINZESS.

LINZESS is a once-daily capsule that helps relieve belly pain as well as overall abdominal symptoms, and lets you have more frequent and complete bowel movements that are easier to pass. The #1 prescribed IBS-C/CIC branded treatment, it can help you proactively manage your symptoms.

WHAT SYMPTOMS OF IBS-C & CIC CAN LINZESS HELP RELIEVE?

IBS-C

Constipation
Belly pain
Overall abdominal symptoms
Infrequent and incomplete bowel movements

CIC

Constipation
Infrequent and incomplete bowel movements

Closed medicine bottle with generic label.

LINZESS WORKS DIFFERENTLY THAN LAXATIVES

LINZESS was the first approved treatment in a class of drugs that work differently than other medications.

HOW LINZESS WORKS

WHEN LINZESS IS TAKEN DAILY, YOUR CONSTIPATION SYMPTOMS MAY BEGIN TO IMPROVE IN ABOUT 1 WEEK

Constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience belly pain and overall abdominal symptom relief in about 1 week, with symptoms typically improving over 12 weeks. If you stop taking LINZESS, your symptoms could return in about 1 week.

SIDE EFFECTS OF LINZESS

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IMPORTANT RISK INFORMATION

Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
You should not give LINZESS to children 6 years to less than 18 years of age. It may harm them.
Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
Breastfeeding or plan to breastfeed. It is not known if LINZESS passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects

LINZESS can cause serious side effects, including diarrhea, the most common side effect, which can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

What is LINZESS?

LINZESS^® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). "Idiopathic" means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

Please also see Medication Guide within Full Prescribing Information.

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IMPORTANT RISK INFORMATION

Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).