HOW LINZESS WORKS
LINZESS CAN HELP PROACTIVELY MANAGE SYMPTOMS OF IBS-C & CIC
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LINZESS isn’t a laxative. It’s a once-daily pill that can help proactively manage symptoms of IBS-C and CIC, including belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) associated with IBS-C.
LINZESS was the first approved treatment in a class of drugs that work differently than other medications. It acts locally in the intestine and is thought to work in 2 ways:
Calms pain-sensing nerves**
Accelerates bowel movements
*Abdominal symptoms were studied in combination, not individually.
**This was seen in animal studies, and the relevance to humans is not known.
![An icon diagram of exposed stomach demonstrating how LINZESS works.](/content/dam/linzess/images/1.1-how-linzess-works-m-belly-pain-accelerate@2x.png)
![Patient story](/content/dam/linzess/images/1.1-how-linzess-works-m-nanquote@2x.jpg)
“After about a week of being on LINZESS, my bowel movements became more regular…and then, my pain started to subside.”
Nan, 54
Prescribed LINZESS for IBS-C
![When can I expect to start seeing my symptoms](/content/dam/linzess/images/1.1-how-linzess-works-m-improve-calendar@2x.png)
WHEN CAN I EXPECT TO START SEEING MY SYMPTOMS IMPROVE WITH LINZESS?
When LINZESS is taken daily, constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience relief of belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) in about 1 week, with symptoms typically improving over 12 weeks.
*Abdominal symptoms were studied in combination, not individually.
WHEN CAN I EXPECT TO START SEEING MY SYMPTOMS IMPROVE WITH LINZESS?
When LINZESS is taken daily, constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience relief of belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) in about 1 week, with symptoms typically improving over 12 weeks.
*Abdominal symptoms were studied in combination, not individually.
YOU COULD PAY AS LITTLE AS $30* FOR 90 OR 30 DAYS OF LINZESS
Whether you start with a 90-day or 30-day prescription, you could be eligible to pay as little as $30* with the LINZESS Savings Program. Talk to a doctor about a 90-day prescription to potentially maximize your savings and minimize trips to the pharmacy.
![You could pay as little as](/content/dam/linzess/images/0.0-homepage-m-90-days-for-30-icon@2x.png)
*Maximum savings limit applies; patient out-of-pocket expense may vary. This offer is available to patients with commercial insurance coverage and a valid LINZESS prescription. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. This offer is not valid for cash-paying patients. Please see Program Terms, Conditions, Privacy Notice, and Eligibility Criteria.