PART 1

On screen: Dian, Age 43, Diagnosed with Chronic Idiopathic Constipation (CIC) in 2011 

Dian: Hi. My name is Dian and I was diagnosed with Chronic Idiopathic Constipation in 2011. 

Dian: My husband, Todd, and I have been married since 2000. We have two kids, Darien and Sage, and we live in Texas. 

Dian: For fun, I like to cook. I cook a variety of dishes. Uh.. my favorite thing to cook is Jamaican and Chinese fusion dishes. Uh.. my daughter is a big soccer fan and she plays in a soccer league and I play with her in the backyard. Also, to relieve stress I do yoga, and I also love to read whatever is on the current fiction list. 

Dian: I've been a flight attendant since 1996. I do both domestic and international traveling; mostly international. I can say I've seen all over the world and I absolutely love my job. 

Dian: Dealing with CIC as a flight attendant is very challenging. I was working 15 to 20 hours a day. I was not eating on a regular schedule, and it was hard to pack really healthy foods to carry on a 15-to-20-day trip, 'cause you're gone for so long. 

Dian: My primary care physician would tell me that I just need to incorporate more fiber into my diet, change my diet, drink lots of water, and also it was because of my work schedule. I've been dealing with it for so long, so I was starting to get worried and more stressed. 

Dian: I would use laxative basically on a daily basis to help with the constipation

Dian: A few years ago I was on a very long flight, and uhm.. I hadn't used the restroom in over a week, so I was leery about going to work. However, I couldn't find anyone to take my trip, so I had to go. About four hours into the flight uhm.. I started to feel really uncomfortable, uhm... a lotta discomfort, and I contacted a coworker and just asked him to just take over my position for me. And I went into the lav, and I was in there for about two hours, and I felt really bad, because I know we had over 250 guests onboard who wanted to use this lav. But I just felt so bad, and that- that's when I decided that ..//..I had to make a change.  

Dian: After my episode on the aircraft, I decided to do some intense research and made an appointment with a GI specialist, who did a series of tests, and I was diagnosed with Chronic Idiopathic Constipation in 2011.

Dian: I'd advise anyone out there suffering with CIC to go see a GI specialist. There's a wealth of information available on the Internet that wasn't available 15 to 20 years ago. There are a lot of support groups, blogs, and just remember that you're not alone and you do not have to suffer by yourself. 

PART 2

On screen: Hear about Dian’s experience with LINZESS^® after this important information.

Text on-screen with voiceover

Narrator: LINZESS^® (linaclotide) is a prescription medication used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) in adults and functional constipation (FC) in children and adolescents 6 to 17 years of age. “Idiopathic” means the cause of the constipation is unknown. It is not known LINZESS is safe and effective in children with functional constipation less than 6 years of age or in children with IBS-C less than 18 years of age.

IMPORTANT RISK INFORMATION

• Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
• Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Please see Important Risk Information at the end of this video.

On screen Dian, Age 43, Diagnosed with Chronic Idiopathic Constipation (CIC) in 2011

Dian: After my diagnosis, the GI specialist and myself, we decided that I would continue with the high-fiber diet, cut out the simple carbs and continue incorporated uhm.. lots of water. 

Dian: In 2013, I went for a follow-up appointment with my GI specialist and he was like, "Hi Dian, I'm so happy to see you, I've been thinking about you and there's this treatment I'd like you to try, it's called LINZESS.

Dian: During my appointment, he explained that LINZESS is approved for adults living with CIC.

Dian: We discussed the potential benefits and risks and we decided that LINZESS would be a good option for me.

On screen Individual results and experiences may vary.

Dian: After two weeks of taking LINZESS, I noticed a change in my bowel movements, I was going to the restroom more frequently and I noticed a change in the consistency of my stool. It wasn't as hard and I felt I could go completely.

Dian: Early on after taking LINZESS, I did experience some diarrhea but after three to four weeks, the diarrhea went away.

Dian: My doctor also told me about all the potential side effects with LINZESS, including gas, stomach-area pain and swelling or a feeling of fullness and pressure in my abdomen.

Dian: Taking LINZESS has become part of my daily routine. I still eat a healthy diet, drink lots of water, stay hydrated. I'm still a flight attendant, fly long hours, long duty day. However, I know that taking my LINZESS with me will help with my bowel movements. 

Text on-screen with voiceover

IMPORTANT RISK INFORMATION

• Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
• Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).
   

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

• If you are pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
• Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take LINZESS and breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects
LINZESS can cause serious side effects, including diarrhea, which is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS in people with IBS-C and CIC include gas, stomach-area (abdomen) pain, and swelling, or a feeling of fullness or pressure in your abdomen (distention).

Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdomen) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information including Boxed Warning and Medication Guide at www.LINZESS.com.

Ask your doctor about LINZESS. For more information, call 1-800-LINZESS.

[On screen]
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