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HOW TO TAKE LINZESS

WHY TAKING LINZESS AS DIRECTED MATTERS

For adults with Irritable Bowel Syndrome with Constipation (IBS-C) or Chronic Idiopathic Constipation (CIC)

Once you’ve been prescribed LINZESS, it’s important to stay on top of your treatment: If you stop taking your medication, your symptoms could return in about a week. Take the medication as recommended by your doctor and keep them informed about your experience with LINZESS.

TAKE LINZESS…

Two-tone pill capsule.

… EVERY DAY For LINZESS to work best, take it every day. This is different from over-the-counter laxatives, which are often taken as needed.

When LINZESS is taken daily, constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience belly pain and overall abdominal symptom relief in about 1 week, with symptoms typically improving over 12 weeks.

Ringing smartphone. Ringing smartphone. Ringing smartphone.

… ONCE A DAY If you miss a dose, take your dose as usual the following day. Do not take 2 doses at the same time to make up for a missed dose.

Empty anatomical stomach.

… ON AN EMPTY STOMACH Take your pill, as prescribed by your doctor, at least 30 minutes before your first meal of the day.

Full glass of water. Full glass of water. Full glass of water.

… WITH APPLESAUCE OR WATER, IF NECESSARY If you have trouble swallowing capsules, carefully open the LINZESS capsule and sprinkle all of the LINZESS beads onto applesauce or into 1 oz. (30mL) of water.

WHAT TO KNOW BEFORE STARTING LINZESS

Want to get off to the right start with LINZESS? Watch this short video where Dr. Darren Brenner shares 4 key points about how to take LINZESS and what to expect in terms of symptom relief and common side effects.

“The purpose of this short video is to provide you with some important clinical information that may assist you in achieving a successful outcome when taking LINZESS.”

Dr. Darren Brenner,
Northwestern University Feinberg School of Medicine

BE PROACTIVE WITH YOUR TREATMENT

Doctor’s stethoscope. Doctor’s stethoscope. Doctor’s stethoscope.

UPDATE YOUR DOCTOR

It’s important to keep your doctor informed about how LINZESS is working for you. Let them know how it may be helping to manage your IBS-C or CIC symptoms and if you’re experiencing any side effects.

Medication bottle with blank label. Medication bottle with blank label. Medication bottle with blank label.

REFILL ON TIME

Your local pharmacy may offer refill reminders—ask your pharmacist about signing up. Can’t make it to the pharmacy for a while? Notify your doctor or pharmacist to ensure you have enough medication. You may also want to check if your pharmacy offers delivery services.

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IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • You should not give LINZESS to children 6 years to less than 18 years of age. It may harm them.
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if LINZESS passes into your breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects

LINZESS can cause serious side effects, including diarrhea, the most common side effect, which can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

What is LINZESS?

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). "Idiopathic" means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

Please also see Medication Guideopen pdf in new tab within Full Prescribing Information.open pdf in new tab

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IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 6 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).